Effect of methanolic extract of Citrus limetta peel on cellular and humoral immune response.

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PMID: Pak J Pharm Sci. 2021 Sep ;34(5(Supplementary)):1861-1866. PMID: 34836851 Abstract Title: Effect of methanolic extract of Citrus limetta peel on cellular and humoral immune response in mice. Abstract: Citrus limetta is well known for its anti-inflammatory, antimicrobial, antifungal, antidiabetic and antioxidant properties. Methanolic extract of Citrus limetta (MECL) was used to assess cellular and humoral immune responses in mice by carrying out cyclophosphamide-induced neutropenia, delayed-type hypersensitivity (DTH), carbon clearance assay, haemagglutination assay (HA) and mice lethality assay. Methanolic extract of Citrus limetta peel was administered orally to mice in two doses 200mg/kg and 400mg/kg.The extract treated groups showed improvement in neutropenia induced by cyclophosphamide and improvement in the WBC profile. Skin thickness was significantly (P
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