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Heath
Alternative Medicine
Formulation effects in the antioxidant activity of extract from the leaves of Cymbopogon citratus.
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<blockquote data-quote="greenmedinfo" data-source="post: 2514"><p>PMID: Molecules. 2021 Jul 27 ;26(15). Epub 2021 Jul 27. PMID: 34361669 Abstract Title: Formulation Effects in the Antioxidant Activity of Extract from the Leaves of(DC) Stapf. Abstract: DC (Stapf.) is a perennial grass and it is distributed around the world. It is used as a condiment for food and beverage flavouring in the form of infusions and decoctions of its dried leaves. Our previous studies have shown antioxidant, anti-inflammatory and gastroprotective activities for the infusion and its phenolic fractions. The aim of the present work was to develop oral dosage forms from aextract to be used as a functional food with antioxidant properties. Initially, an essential oil-free infusion was prepared, lyophilized and characterized by HPLC-PDA. Total phenols were quantified with the Folin-Ciocalteu method and the antioxidant activity was assessed by DPPH assay. Gelatine capsules containing the extract with different excipients, selected after DSC and IR trials, were prepared. A formulation exhibiting better antioxidant behaviour in a gastric environment was attained. These results suggest that the proposed formulation for this extract could be a valuable antioxidant product and, consequently, make an important contribution to "preventing" and minimizing diseases related to oxidative stress conditions. </p><p><a href="https://www.greenmedinfo.com/article/formulation-effects-antioxidant-activity-extract-leaves-cymbopogon-citratus" target="_blank">read more</a></p></blockquote><p></p>
[QUOTE="greenmedinfo, post: 2514"] PMID: Molecules. 2021 Jul 27 ;26(15). Epub 2021 Jul 27. PMID: 34361669 Abstract Title: Formulation Effects in the Antioxidant Activity of Extract from the Leaves of(DC) Stapf. Abstract: DC (Stapf.) is a perennial grass and it is distributed around the world. It is used as a condiment for food and beverage flavouring in the form of infusions and decoctions of its dried leaves. Our previous studies have shown antioxidant, anti-inflammatory and gastroprotective activities for the infusion and its phenolic fractions. The aim of the present work was to develop oral dosage forms from aextract to be used as a functional food with antioxidant properties. Initially, an essential oil-free infusion was prepared, lyophilized and characterized by HPLC-PDA. Total phenols were quantified with the Folin-Ciocalteu method and the antioxidant activity was assessed by DPPH assay. Gelatine capsules containing the extract with different excipients, selected after DSC and IR trials, were prepared. A formulation exhibiting better antioxidant behaviour in a gastric environment was attained. These results suggest that the proposed formulation for this extract could be a valuable antioxidant product and, consequently, make an important contribution to "preventing" and minimizing diseases related to oxidative stress conditions. [URL='https://www.greenmedinfo.com/article/formulation-effects-antioxidant-activity-extract-leaves-cymbopogon-citratus']read more[/URL] [/QUOTE]
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Alternative Medicine
Formulation effects in the antioxidant activity of extract from the leaves of Cymbopogon citratus.
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