PMID: Br J Nutr. 2021 Dec 16:1-25. Epub 2021 Dec 16. PMID: 34913420 Abstract Title: Plasma vitamin B12 concentration is positively associated with cognitive development in healthy Danish 3-year-old children; the SKOT cohort studies. Abstract: Adequate vitamin B12 and folate concentrations are essential for neural development in early childhood but studies in well-nourished children are lacking. We investigated the relation between plasma vitamin B12 and folate at 9 and 36 months and psychomotor development at 36 months in well-nourished Danish children. Subjects from the SKOT cohorts with vitamin B12 measurement and completed Ages and Stages Questionnaire (ASQ-3) at 36 months were included (n=280). Dietary intake, vitamin B12- and folate concentrations were collected at 9 and 36 months, and ASQ-3 was assessed at 36 months. Associations between vitamin B12 and folate at 9 and 36 months and ASQ-3 were analyzed using regression models. Associations between diet and vitamin B12 were also investigated. No children had insufficient vitamin B12(
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