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Message: [QUOTE="greenmedinfo, post: 3691"] PMID: Mar Drugs. 2021 Jul 26 ;19(8). Epub 2021 Jul 26. PMID: 34436254 Abstract Title: Polar Lipids Composition, Antioxidant and Anti-Inflammatory Activities of the Atlantic Red Seaweed. Abstract: Yamada, 1941, is a red seaweed widely used for food in Japan and Korea which was recorded on the Atlantic Coast of Europe about twenty years ago. This seaweed presents eicosapentaenoic acid (EPA) and other polyunsaturated fatty acids (PUFAs) in its lipid fraction, a feature that sparked the interest on its potential applications. In seaweeds, PUFAs are mostly esterified to polar lipids, emerging as healthy phytochemicals. However, to date, these biomolecules are still unknown for. The present work aimed to identify the polar lipid profile of, using modern lipidomics approaches based on high performance liquid chromatography coupled to high resolution mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS). The health benefits of polar lipids were identified by health lipid indices and the assessment of antioxidant and anti-inflammatory activities. The polar lipids profile identified fromincluded 205 lipid species distributed over glycolipids, phospholipids, betaine lipids and phosphosphingolipids, which featured a high number of lipid species with EPA and PUFAs. The nutritional value ofhas been shown by its protein content, fatty acyl composition and health lipid indices, thus confirmingas an alternative source of protein and lipids. Some of the lipid species assigned were associated to biological activity, as polar lipid extracts showed antioxidant activity evidenced by free radical scavenging potential for the 2,2'-azino-bis-3-ethyl benzothiazoline-6-sulfonic acid (ABTS) radical (ICca. 130.4μg mL) and for the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical (ICca. 129.1μg mL) and anti-inflammatory activity by inhibition of the COX-2 enzyme (ICca. 33µg mL). Both antioxidant and anti-inflammatory activities were detected using a low concentration of extracts. This integrative approach contributes to increase the knowledge ofas a species capable of providing nutrients and bioactive molecules with potential applications in the nutraceutical, pharmaceutical and cosmeceutical industries. [URL='https://www.greenmedinfo.com/article/polar-lipids-composition-antioxidant-and-anti-inflammatory-activities-atlantic']read more[/URL] [/QUOTE]

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