cancer

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    Improving anti-tumor outcomes for colorectal cancer therapy through in situ thermosensitive gel loading harmine.

    PMID: Am J Transl Res. 2020 ;12(5):1658-1671. Epub 2020 May 15. PMID: 32509167 Abstract Title: Improving anti-tumor outcomes for colorectal cancer therapy throughthermosensitive gel loading harmine. Abstract: Colorectal cancer is a common malignant tumor that seriously endangers human health...
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    Structure-activity insights of harmine targeting DNA, ROS inducing cytotoxicity with PARP mediated apoptosis against cervical cancer, anti-biofilm for

    PMID: J Biomol Struct Dyn. 2021 Jan 22:1-23. Epub 2021 Jan 22. PMID: 33480316 Abstract Title: Structure-activity insights of harmine targeting DNA, ROS inducing cytotoxicity with PARP mediated apoptosis against cervical cancer, anti-biofilm formation andtherapeutic study. Abstract: Harmine...
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    Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1.

    PMID: PLoS One. 2021 ;16(2):e0247652. Epub 2021 Feb 24. PMID: 33626096 Abstract Title: Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1. Abstract: Breast cancer is the leading cause of cancer-related deaths in the United States. The majority of...
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    Serotonergic hallucinogens/psychedelics could be promising treatments for depressive and anxiety disorders in end-stage cancer.

    PMID: BMC Psychiatry. 2019 10 28 ;19(1):321. Epub 2019 Oct 28. PMID: 31660905 Abstract Title: Serotonergic hallucinogens/psychedelics could be promising treatments for depressive and anxiety disorders in end-stage cancer. Abstract: In a recent issue of the BMC Psychiatry, the evidence of...
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    Harmine hydrochloride mediates the induction of G2/M Cell cycle arrest in breast cancer cells.

    PMID: Molecules. 2021 Nov 5 ;26(21). Epub 2021 Nov 5. PMID: 34771123 Abstract Title: Harmine Hydrochloride Mediates the Induction of G2/M Cell Cycle Arrest in Breast Cancer Cells by Regulating the MAPKs and AKT/FOXO3a Signaling Pathways. Abstract: Breast cancer (BC) is one of the most common...
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    The role of psilocybin-assisted psychotherapy to support patients with cancer.

    PMID: J Holist Nurs. 2021 Sep 6:8980101211039086. Epub 2021 Sep 6. PMID: 34482761 Abstract Title: The Role of Psilocybin-Assisted Psychotherapy to Support Patients With Cancer: A Critical Scoping Review of the Research. Abstract: Treatments for addressing psychiatric mental health issues in...
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    Therapeutic potential of ursolic acid in cancer and diabetic neuropathy diseases.

    PMID: Int J Mol Sci. 2021 Nov 10 ;22(22). Epub 2021 Nov 10. PMID: 34830043 Abstract Title: Therapeutic Potential of Ursolic Acid in Cancer and Diabetic Neuropathy Diseases. Abstract: Ursolic acid (UA) is a pentacyclic triterpenoid frequently found in medicinal herbs and plants, having...
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    Emodin induces apoptosis and suppresses non-small-cell lung cancer growth via downregulation of sPLA2-IIa.

    PMID: Phytomedicine. 2021 Oct 1:153786. Epub 2021 Oct 1. PMID: 34785104 Abstract Title: Emodin induces apoptosis and suppresses non-small-cell lung cancer growth via downregulation of sPLA2-IIa. Abstract: BACKGROUND: Lung cancer has become the principal cause of cancer-related deaths. Emodin...
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    Piperine analogs arrest c-myc gene leading to downregulation of transcription for targeting cancer.

    PMID: Sci Rep. 2021 Nov 25 ;11(1):22909. Epub 2021 Nov 25. PMID: 34824301 Abstract Title: Piperine analogs arrest c-myc gene leading to downregulation of transcription for targeting cancer. Abstract: G-quadruplex (G4) structures are considered a promising therapeutic target in cancer. Since...
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    Vinehealth, offering digital support for cancer patients and SaaS for R&D, gets $5.5M to launch in the US

    Vinehealth, a 2018-founded, London-based digital health startup that’s built an app which offers personalized support for cancer patients while also making it easier to gather patient-reported outcome (PRO) data, including for drug development and clinical trials, has closed a $5.5 million seed...
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    Extract of Pogostemon cablin possesses potent anticancer activity against colorectal cancer cells.

    PMID: Evid Based Complement Alternat Med. 2020 ;2020:9758156. Epub 2020 Sep 9. PMID: 32963578 Abstract Title: Extract ofPossesses Potent Anticancer Activity against Colorectal Cancer Cells In Vitro and In Vivo. Abstract: (PCa), an herb used in traditional Chinese medicine, is routinely used...
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    Extraction of phenolic compounds from the shells of pecan nuts with cytotoxic activity through apoptosis against the colon cancer cell line HT-29.

    PMID: J Food Sci. 2021 Nov 3. Epub 2021 Nov 3. PMID: 34730241 Abstract Title: Extraction of phenolic compounds from the shells of pecan nuts with cytotoxic activity through apoptosis against the colon cancer cell line HT-29. Abstract: The water extraction of phenolic compounds from two...
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    Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.

    PMID: Mol Med Rep. 2019 Sep ;20(3):2805-2811. Epub 2019 Jul 11. PMID: 31322235 Abstract Title: Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ. Abstract: Bavachinin (BNN), one of the main active ingredients of Psoraleacorylifolia, can activate...
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    Bavachinin mitigates DMH induced colon cancer in rats by altering p53/Bcl2/BAX signaling associated with apoptosis,

    PMID: Biotech Histochem. 2021 Apr ;96(3):179-190. Epub 2020 Jul 15. PMID: 32664769 Abstract Title: Bavachinin mitigates DMH induced colon cancer in rats by altering p53/Bcl2/BAX signaling associated with apoptosis. Abstract: Bavachinin is a flavanone obtained from the Chinese herb...
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    Bavachinin led to the induction of G2/M cell cycle arrest in non-small-cell lung cancer cells.

    PMID: Molecules. 2021 Aug 25 ;26(17). Epub 2021 Aug 25. PMID: 34500594 Abstract Title: Induction of G2/M Cell Cycle Arrest via p38/p21-Dependent Signaling Pathway Activation by Bavachinin in Non-Small-Cell Lung Cancer Cells. Abstract: Lung cancer is the most commonly diagnosed malignant...
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    Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer.

    PMID: Aging (Albany NY). 2021 Nov 25 ;13(undefined). Epub 2021 Nov 25. PMID: 34821587 Abstract Title: Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling. Abstract: Pancreatic cancer is an extremely malignant digestive tract...
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    A review of kaempferol, myricetin and fisetin in prostate and bladder cancer.

    PMID: Nutrients. 2021 Oct 23 ;13(11). Epub 2021 Oct 23. PMID: 34836005 Abstract Title: Kaempferol, Myricetin and Fisetin in Prostate and Bladder Cancer: A Systematic Review of the Literature. Abstract: Prostate and bladder cancer represent the two most frequently diagnosed genito-urinary...
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    Naringenin inhibits human breast cancer cells MDA-MB-231.

    PMID: Cell Mol Biol (Noisy-le-grand). 2021 Sep 29 ;67(2):8-13. Epub 2021 Sep 29. PMID: 34817344 Abstract Title: Naringenin inhibits human breast cancer cells (MDA-MB-231) by inducing programmed cell death, caspase stimulation, G2/M phase cell cycle arrest and suppresses cancer metastasis...
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    Evidence of immunogenic cancer cell death induced by honey-processed Astragalus polysaccharides in vitro and in vivo.

    PMID: Exp Cell Res. 2021 Nov 23:112948. Epub 2021 Nov 23. PMID: 34826423 Abstract Title: Evidence of immunogenic cancer cell death induced by honey-processed Astragalus polysaccharides in vitro and in vivo. Abstract: Honey-processed Astragalus is a dosage form of Radix Astragalus mixed with...
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    Berberine improves irinotecan-induced intestinal mucositis without impairing the anti-colorectal cancer efficacy of irinotecan.

    PMID: Front Pharmacol. 2021 ;12:774560. Epub 2021 Nov 2. PMID: 34795594 Abstract Title: Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterialβ-glucuronidase. Abstract: Irinotecan (CPT11), a...