injury

PMID: J Sci Food Agric. 2021 Oct 24. Epub 2021 Oct 24. PMID: 34689333 Abstract Title: Laminaria japonica fucoidan ameliorates cyclophosphamide-induced liver and kidney injury possibly by regulating Nrf2/HO-1 and TLR4/NF-κB signaling pathways. Abstract: BACKGROUND: During clinical practice...

PMID: Mol Med Rep. 2021 Nov ;24(5). Epub 2021 Sep 9. PMID: 34498711 Abstract Title: polysaccharide protects rats and cardiomyocytes against ischemia/reperfusion injury via Nrf2 activation through autophagy inhibition. Abstract: The irreversible loss of cardiomyocytes is mainly the result of...

PMID: Front Pharmacol. 2021 ;12:689880. Epub 2021 Nov 15. PMID: 34867315 Abstract Title: Low-Dose Piperlongumine Rescues Impaired Function of Endothelial Progenitor Cells and Reduces Cerebral Ischemic Injury in High-Fat Diet-Fed Mice. Abstract: It is of great clinical significance to develop...

PMID: Res Pharm Sci. 2020 Dec ;15(6):541-550. Epub 2020 Nov 27. PMID: 33828597 Abstract Title: Harmine protects mercuric chloride kidney-induced injury by antioxidant activity in male mice: a biochemical and histological study. Abstract: Background and purpose: Mercuric chloride (Merc) can...

PMID: Antioxidants (Basel). 2021 Oct 15 ;10(10). Epub 2021 Oct 15. PMID: 34679755 Abstract Title: Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the...

PMID: Neuroreport. 2021 06 9 ;32(9):815-823. PMID: 33994527 Abstract Title: Salvianolic acid B protects against MPP+-induced neuronal injury via repressing oxidative stress and restoring mitochondrial function. Abstract: Maintaining normal conditions in the mitochondria and repressing...

PMID: J Toxicol Sci. 2021 ;46(5):199-207. PMID: 33952797 Abstract Title: Salvianolic acid B attenuated cisplatin-induced cardiac injury and oxidative stress via modulating Nrf2 signal pathway. Abstract: Cardiovascular complications have been well documented as the downside to conventional...

PMID: Int Urol Nephrol. 2021 Nov 25. Epub 2021 Nov 25. PMID: 34825305 Abstract Title: Allicin protects against renal ischemia-reperfusion injury by attenuating oxidative stress and apoptosis. Abstract: BACKGROUND: Studies have demonstrated that allicin may play critical roles in the...

PMID: Kaohsiung J Med Sci. 2021 Nov 22. Epub 2021 Nov 22. PMID: 34806822 Abstract Title: Emodin alleviates sepsis-mediated lung injury via inhibition and reduction of NF-kB and HMGB1 pathways mediated by SIRT1. Abstract: Inflammation plays an important role during sepsis, and excessive...

PMID: Eur J Pharmacol. 2021 Nov 15:174603. Epub 2021 Nov 15. PMID: 34793771 Abstract Title: Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission. Abstract: Acute kidney injury (AKI) is a serious threat to human health. Clinically...

PMID: Inflammation. 2021 Nov 17. Epub 2021 Nov 17. PMID: 34787801 Abstract Title: Emodin Attenuates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Dependent Pyroptosis Signaling Pathway In vitro and In vivo. Abstract: Emodin, the effective component of the traditional Chinese...

PMID: Nutrients. 2021 Nov 15 ;13(11). Epub 2021 Nov 15. PMID: 34836346 Abstract Title: A Comparative Study of the Hepatoprotective Effect ofExtract (CA-HE50) on Lipopolysaccharide/d-galactosamine-Induced Acute Liver Injury in C57BL/6 Mice. Abstract: Acute liver failure (ALF) refers to the...

PMID: Bioengineered. 2021 Dec ;12(2):9332-9340. PMID: 34806937 Abstract Title: Stigmasterol alleviates interleukin-1beta-induced chondrocyte injury by down-regulatingsterol regulatory element binding transcription factor 2 to regulateferroptosis. Abstract: Stigmasterol (STM), one of the main...

PMID: Bioengineered. 2021 12 ;12(1):7794-7804. PMID: 34704542 Abstract Title: Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage. Abstract: Early brain injury, characterized by massive cell apoptosis or death, is identified as a critical...

PMID: Food Funct. 2021 Nov 25. Epub 2021 Nov 25. PMID: 34821232 Abstract Title: Baicalin inhibits APEC-induced lung injury by regulating gut microbiota and SCFA production. Abstract: Baicalin is a plant-derived flavonoid fromGeorgi with multiple bioactivities and has a protective effect...

PMID: Int Immunopharmacol. 2021 Sep ;98:107897. Epub 2021 Jun 25. PMID: 34182243 Abstract Title: Patchouli alcohol ameliorates acute liver injury via inhibiting oxidative stress and gut-origin LPS leakage in rats. Abstract: Alcoholism represents a predisposing factor for liver-related...

PMID: Biochem Pharmacol. 2020 12 ;182:114260. Epub 2020 Oct 2. PMID: 33017576 Abstract Title: β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance. Abstract: Ulcerative colitis...

PMID: Exp Ther Med. 2019 May ;17(5):3335-3342. Epub 2019 Mar 12. PMID: 30988709 Abstract Title: Effect ofβ-patchoulene on cerebral ischemia-reperfusion injury and the TLR4/NF-κB signaling pathway. Abstract: β-patchoulene (β-PAE), an active constituent of theneuroprotective effect ofβ-PAE and...

PMID: Int J Mol Sci. 2019 Aug 21 ;20(17). Epub 2019 Aug 21. PMID: 31438541 Abstract Title: Pachypodol, a Methoxyflavonoid Isolated fromBentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation. Abstract: Oxidative stress has been...

PMID: Front Cell Dev Biol. 2021 ;9:693533. Epub 2021 Jul 22. PMID: 34368142 Abstract Title: Patchouli Alcohol Improves the Integrity of the Blood-Spinal Cord Barrier by Inhibiting Endoplasmic Reticulum Stress Through the Akt/CHOP/Caspase-3 Pathway Following Spinal Cord Injury. Abstract...